How to Use Psilocybin Microdoses and Lion's Mane to Treat Mental and Cognitive Health Issues

One of our best products is microdoses of psilocybin and Lion’s Mane, specifically designed to address various mental and neuronal health issues. We are proud to produce a unique strain called Sengio, which stands out for its smoothness and specific neurological effects. This presentation explores the therapeutic properties of our psilocybin microdoses and Lion’s Mane mushroom, backed by recent scientific studies.

1. Psilocybin Microdoses: A New Therapeutic Opportunity

Sengio Strain: What Sets Us Apart 

The Sengio strain is unique. While traditional psilocybin available on the market can be potent and, at times, difficult to regulate in microdosing treatments, Sengio is characterized by its smoothness and modulatory properties that act directly on neuronal functions, offering a safer and more manageable treatment.

• Direct Action in the Brain: Psilocybin from the Sengio strain works effectively with serotonin receptors (5-HT2A) in the brain, promoting neuroplasticity and facilitating the growth of new neural connections.

• Smoothness and Controlled Effects: Unlike other strains, Sengio allows for more controlled microdoses, reducing the likelihood of unwanted side effects, such as anxiety or overstimulation, while providing deep therapeutic benefits.

  
  

Therapeutic Uses of Psilocybin in Microdoses

The use of psilocybin has shown promising results in several mental health fields, especially in the treatment of:

• Anxiety and Mood Disorders: A clinical trial conducted by Johns Hopkins Medicine highlighted that psilocybin microdoses can help reduce anxiety symptoms in patients with severe illnesses.

• Post-Traumatic Stress Disorder (PTSD): Preliminary studies suggest that psilocybin microdoses, by promoting neuroplasticity, can help patients with PTSD reprogram damaged neural pathways.

• Chronic Fatigue and Stress: Various studies, including one by Maastricht University, have confirmed its ability to enhance focus, reduce stress, and alleviate mental exhaustion.

  
  

2. Lion’s Mane: Neurocognitive Support and Cellular Repair

The Lion’s Mane mushroom (Hericium erinaceus) has been recognized in traditional Asian medicine for centuries, and modern science has validated its use for its neuroprotective and cognitive effects.

Therapeutic Properties

• Neurogenesis: Lion’s Mane stimulates the production of nerve growth factor (NGF), which helps regenerate neurons and myelin, according to a study in Phytotherapy Research. This makes it an attractive option for individuals looking to improve memory and cognitive function and prevent neurodegenerative diseases like Alzheimer’s and dementia.

• Cognitive Function Improvement: Clinical trials have shown that consuming Lion’s Mane for four weeks significantly improved cognitive test scores in older adults with mild cognitive impairment.

• Reduction of Anxiety and Depression: The same study showed that this mushroom could have positive effects on mood by reducing symptoms of anxiety and depression, likely due to its neurotrophic effects.

  
  

Combined Use of Sengio Psilocybin and Lion’s Mane

Combining Sengio psilocybin microdoses with Lion’s Mane has shown a unique synergistic effect in enhancing neuroplasticity and cognitive function.

• Neuroprotection and Regeneration: While psilocybin enhances the brain’s ability to create new neural connections, Lion’s Mane supports the regeneration of damaged neurons, making it an effective combination for treating neurocognitive disorders.

• Stress Reduction and Mood Enhancement: Both products work together to promote a more balanced mental state, reducing anxiety and stress while enhancing mental clarity.

  
  

3. Clinical Applications and Medical Considerations

In a clinical setting, both psilocybin microdoses and Lion’s Mane extract have the potential to be used as complementary treatments for patients with conditions such as depression, anxiety, cognitive problems, or neurological deterioration.

• Suggested Dose of Sengio Psilocybin: Under medical supervision, a microdose of 0.1 to 0.3 grams per day is recommended to avoid any possible interactions with other medications or treatments.

• Suggested Dose of Lion’s Mane: The most commonly used dose in clinical studies to improve cognitive function and neuronal regeneration is between 500 mg and 1 gram per day.

  
  

The Sengio psilocybin and Lion’s Mane mushroom offer innovative, science-backed therapeutic solutions to improve patients' mental and neuronal health. These substances can be a valuable tool in treating emotional, cognitive, and neurological disorders with a natural and well-tolerated approach.

We would be delighted to discuss these benefits further and answer any questions you may have about our microdoses and the unique strain we’ve developed.

Review our post about drug contraindications.

References:

1. Carhart-Harris RL, et al. "Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms." JAMA Psychiatry, 2020.

2. Griffiths, R.R., et al. "Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial." Johns Hopkins Medicine, 2016.

3. Ross, S., et al. "Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: A randomized controlled trial." Journal of Psychopharmacology, 2016.

4. Kuypers, K.P.C., et al. "Microdosing psychedelics: More questions than answers? An overview and suggestions for future research." Journal of Psychopharmacology, 2019.

5. Mori, K., et al. "Neurotrophic effects of the edible mushroom Hericium erinaceus (Yamabushitake) in vitro and in vivo." Phytotherapy Research, 2010.

6. Nagano, M., et al. "Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake." Biomedical Research, 2010.